Honing the Health Message on BRCA Mutations

Honing the health message on BRCA mutations.

Angelina Jolie’s announcement that she had undergone a double mastectomy to ward off potential tumors induced by her BRCA1 mutation served as what Kenneth Offit, MD, called a teachable moment. “Public figures can have seismic impacts on health communication when they speak about their own experiences,” said Offit, chief of the Clinical Genetics Service at the Memorial Sloan–Kettering Cancer Cen...

Olaparib and somatic BRCA mutations

Effect of BRCA germline mutations on breast cancer prognosis

BACKGROUND The contribution of BRCA germline mutational status to breast cancer patients' prognosis is unclear. We aimed to systematically review and perform meta-analysis of the available evidence of effects of BRCA germline mutations on multiple survival outcomes of breast cancer patients as a whole and in specific subgroups of interest, including those with triple negative breast cancer, tho...

BRCA mutations in prostate cancer patients.

Honing in on enteric fever

The use of metabolomics could lead to improved diagnostics for enteric fever.